Avicel PH
Microcrystalline Cellulose, NF, Ph. Eur., JP

The introduction of Avicel PH was a catalyst for the pharmaceutical industry’s conversion to direct compression tablet technology, creating new levels of manufacturing efficiency. Today’s Avicel PH continues to set new standards, with enhanced grades designed to boost productivity and meet any formulation challenge.

Avicel HFE
Microcrystalline Cellulose, NF, Ph. Eur., JP and mannitol, USP, Ph. Eur., JP

Avicel HFE-102 is a new, proprietary co-spray dried MCC/mannitol excipient.  The co-processing of MCC and mannitol creates a synergistic functionality, providing superior benefits versus the use of individual or dry-blended components.  Avicel HFE-102 offers improvements in flow, compaction, and disintegration properties compared to traditional MCC grades.  The product also exhibits less sensitivity to lubrication.

Avicel CE
Microcrystalline Cellulose and Guar Gum
 
The superior organoleptic performance of Avicel CE-15 in chewable tablets results in dramatic differences for end users, primarily in the areas of overall sensory experience and perceived taste, when compared to other tablet binders.  When using Avicel CE-15, the user experiences: less grittiness, reduced tooth packing, minimal chalkiness, creamier mouthfeel, and improved overall palatability. 

	Product Grades	Nominal Particle Size, µm	Moisture, %	Loose Bulk Density, g/cc
Wet Granulation	Avicel PH-101	50	3.0 to 5.0	0.26 - 0.31
Direct Compression	Avicel PH-102	100	3.0 to 5.0	0.28 - 0.33
	Avicel HFE*-102	100	NMT*** 5.0	0.28 - 0.33
Superior Compactibility	Avicel PH-105	20	NMT 5.0	0.20 - 0.30
Superior Flow	Avicel PH-102 SCG**	150	3.0 to 5.0	0.28 - 0.34
	Avicel PH-200	180	2.0 to 5.0	0.29 - 0.36
High Density	Avicel PH-301	50	3.0 to 5.0	0.34 - 0.45
	Avicel PH-302	100	3.0 to 5.0	0.35 - 0.46
Low Moisture	Avicel PH-103	50	NMT 3	0.26 - 0.31
	Avicel PH-113	50	NMT 2	0.27 - 0.34
	Avicel PH-112	100	NMT 1.5	0.28 - 0.34
	Avicel PH-200 LM	180	NMT 1.5	0.30 - 0.38
Mouthfeel Improvement	Avicel CE-15	75	NMT 8	N/A
	*High Functionality Excipient **Special Coarse Grade		***Not More Than