Ac-Di-Sol
Croscarmellose Sodium, NF, Ph Eur, JPE
Ac-Di-Sol super disintegrant facilitates rapid disintegration and drug dissolution at low use levels in tablets, capsules, granules, and other rapidly disintegrating dosage forms. Ac-Di-Sol is recognized for superior quality, consistency, and stability and is the standard by which super disintegrants are compared.
Applications
Direct Compression
Wet Granulation
Dry Granulation
Encapsulation
Attributes and Benefits
Ac-Di-Sol’s versatility allows it to be used in all tablet and capsule formulations. Its unique fibrous nature gives it outstanding water wicking capabilities and its cross-linked chemical structure creates an insoluble, hydrophilic, highly absorbent material, resulting in excellent swelling properties. This dual functionality translates into superior disintegration characteristics, when compared to other super disintegrants, even at very low use levels and high tablet hardness. Studies have shown that Ac-Di-Sol delivers superior performance in wet granulation formulations, and is the only distintegrant that is effective intra- and extra-granularly.
Product Brochure
For a copy of a product brochure, please click here.
Application Bulletins
For a copy of an application/concept bulletin please click on one of the applications below.
Ac-Di-Sol efficacy in wet granulation
Ac-Di-Sol impact on dissolution: a comparative study