Avicel PH
Microcrystalline Cellulose, NF, Ph Eur, JP, BP
The introduction of Avicel PH enabled the first large-scale conversion to direct compression tablet production, creating new levels of manufacturing efficiency. Today’s Avicel PH continues to set new standards, with enhanced grades designed to boost productivity and meet any formulation challenge.
Large-particle Avicel PH-200 and higher density grades Avicel PH-301 and Avicel PH-302 boost productivity by improving flowability and enabling larger batch sizes. We offer a wide range of Avicel grades to meet all formulation needs.
Applications
Direct Compression
Dry Granulation
Wet Granulation
Extrusion-Spheronization
Encapsulation
Attribute and Benefits
Avicel PH’s unique properties make it an indispensable formulation tool. It is the excipient of choice for direct compression formulations, lending superior compactibility, drug carrying capacity, and rapid disintegration. These properties also benefit dry granulation processes such as roller compaction or slugging. Avicel acts as an auxiliary binder in wet granulation, helps control wet mass consistency, reduces screen blockage, and promotes uniform, rapid drying. Avicel is an excellent extrusion-spheronization aid. When included in capsule formulations, Avicel improves flow, facilitates plug formation, and aids capsule disintegration.
Product Brochure
For a copy of a product brochure, please click here.
For a copy of an application/concept bulletin please click on the application below.
Compaction simulation accelerates tablet development and scale-up
Loose Bulk Density Analysis
Loose bulk density is a fundamental parameter that helps characterize attributes such as flow, tablet size and blending characteristics.
Although a simple analysis, LBD analysis requires a standard consistent approach. It is critical to follow specific techniques while performing the LBD analysis of microcrystalline cellulose to obtain accurate, reliable, reproducible results.
To help our customers achieve the desired results, FMC BioPolymer has produced a video of this analysis.
Click here to receive a copy of the video.